LUBRICATING OIL REMAINING USEFUL LIFE PREDICTION USING MULTI-OUTPUT GAUSSIAN PROCESS REGRESSION



CD105 (endoglin)-negative murine mesenchymal stromal cells define a new multipotent subpopulation with distinct differentiation and immunomodulatory capacities.

Administration of in vitro expanded mesenchymal stromal cells (MSCs) represents a promising therapy for regenerative medicine and autoimmunity.Both mouse and human MSCs ameliorate autoimmune disease in Fittings syn-, allo- and xenogeneic settings.However, MSC preparations are heterogeneous which impairs their therapeutic efficacy and endorses varia

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Regulatory Dynamics of Tet1 and Oct4 Resolve Stages of Global DNA Demethylation and Transcriptomic Changes in Reprogramming

Summary: Reprogramming somatic cells into induced pluripotent stem cells (iPSCs) involves the reactivation of endogenous pluripotency genes and global DNA demethylation, but temporal resolution of these events using existing markers is limited.Here, we generate murine transgenic lines harboring reporters for the 5-methylcytosine dioxygenase Tet1 an

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